WHO Patient Safety Programme started with Clean Care Safe Care. The first important matter was to improve hand hygiene in order to reduce hospital infections. The main goal was challenge 1. To Reduce Health Care Associated Infections. The challenge 2. WHO Safe Surgery Saves Lives and Implementation of Surgical Safety Checklist. New England Medical Journal published a research done in Holland 2010 that this checklist reduces surgical and anaesthesia complications 33 % and deaths related to surgeries 50 %. The example comes from the aviation world. As pilot checks all monitors and parameters and that routine schedules have been done before flying in the same way all should be checked before surgeries. In giving medicines intravenously there have been many practices to be changed in order to guarantee patient safety. Strong antibiotics are not supposed to be given as a bolus but a stoosis. Intravenous therapy and medication in improving the quality of patient care was in programme in 2007. Strict sterility is needed in handling iv.cannulas, iv.sets and iv.bags or bottles.